IT Operations and Security Engineer

IT Operations and Security Engineer

At Sage Bionetworks, we believe that we can learn more by learning from each other. By improving the way scientists collaborate, we help to make science more effective. We partner with researchers, patients, and healthcare innovators to drive collaborative data-driven science to improve our understanding of human health and disease. The technology platform team at Sage is developing open technology systems and tools to serve as a public resource for the scientific community. Our platform has already been used to support a number of high profile scientific studies in oncology, neurodegenerative, neuropsychological, and other disease areas.


Are you the type of person who enjoys engaging with a diverse group of scientists, engineers, and product designers to develop and deliver new technologies? We are recruiting Engineer / IT professional for a full time position or long term contract role who can help scale our infrastructure to support a growing number of users and partners. A key aspect of this role is an emphasis on improving the organization’s security posture relevant to HIPAA and other regulations for managing PHI and other sensitive biomedical research data.


What you’ll be doing:

  • Take a lead role in ensuring engineering practices and Sage technology products meet the security, compliance, and quality needs of the organization, and of our partners.
  • Lead an effort to meet our increasing regulatory and compliance requirements around management of human health research data under HIPAA and other relevant regulations through formal certification under a program such as HITRUST.
  • Represent Sage in interactions with security professionals in our partner organizations, and coordinate interactions with external regulators and auditors.
  • Evolve and maintain a continuous automated release process for Sage technology products.
  • Define appropriate uptime, performance, and other operational metrics for back-end systems, and develop monitoring and reporting systems to ensure they are met on continuous basis.
  • Define and ensure quality standards are met for software releases by developing appropriate test plans and release processes.
  • Help define the platform team roadmap and architecture though assessments of external cloud computing services and other technologies.


We’d love to hear from you if you:

  • Have a BS in relevant technical field.
  • Have experience helping organizations meet security and compliance requirements in regulated environments. Prior experience working with biomedical data under regulations such as HIPAA strongly preferred.
  • Have at least 5 years of experience provisioning, maintaining, and optimizing use of IT resources for an organization. Proven experience developing and deploying new technologies in rapidly changing start-up environment preferred.
  • Are strongly proficient in AWS and other public cloud infrastructures, and have a track record helping organizations migrate or develop services on top of IaaS and PaaS platforms.
  • Are proficient in systems administration across a variety of operating systems and environments.
  • Are able to effectively manage multiple complex projects in parallel, working with different stakeholders and timelines to meet company objectives.


About Sage Bionetworks:

Sage Bionetworks ( is a leading nonprofit biomedical research organization dedicated to improving patient outcomes and furthering our understanding of human diseases.  We focus on integrating diverse clinical, genomic, imaging, and real-time sensor data to better predict disease progression and response to interventions.  Sage was founded to pioneer open approaches to advancing biomedical research. We are based in Seattle, US and collaborate broadly throughout the world.

  • 20 person professional technology development team embedded in a 70 person research institute with world class experts in genomics, bioinformatics, statistics, and computational biology
  • Entrepreneurial environment and freedom to rapidly develop technological solutions to complex problems
  • Collaborative environment working with leading academic and industry partners

Sage Bionetworks embraces diversity and equity. We are committed to bringing the right talent to our team. We offer competitive compensation and a comprehensive benefits package, including employer supported health insurance and transportation benefits, and an employer matched 403(B) plan.

Apply here. 

Current Positions

Computational Oncology

The Computational Biology group focuses on developing integrative probabilistic models for prediction of disease phenotypes and validating of hypotheses generated by novel methodologies. Currently opportunities include: positions in Oncology focused on conducting original research in analyzing large-scale high dimensional genomics data to develop predictive models of cancer phenotypes. Positions in collaboration with the recently merged Sage/DREAM effort, focused on designing and implementing crowd-sourced collaborative challenges around cancer phenotype prediction problems. Positions in stem cell bioinformatics with a focus on development of the data and analysis bioinformatics portal for the Progenitor Cell Biology Consortium, as well as research projects on modeling molecular mechanisms underlying stem cell differentiation.

Digital Health

Sage Bionetworks’ digital health program is designed to improve disease characterization through the use of sensor-based technologies and bi-directional feedback to improve health monitoring and provide quantitative metrics to assess disease impact on health and on quality of life. We maximize the insights gained from these efforts by providing them through Synapse, a collaborative compute platform. Our mHealth team includes expertise in software engineering (both iOS and Android), clinical study design and development, data governance and data analysis. We are actively involved in projects across a range of disease areas and within the Precision Medicine Initiative.

Neurodegenerative Research

An overarching goal of the Neurodegenerative Research (NDR) group is to improve understanding of the molecular mechanisms of neurodegeneration via computational analyses of high-dimensional genomic data-sets. Our group leads analyses of such data in consortia focused on Alzheimer’s Disease (AD) and related neurodegenerative disorders, including AMP-AD and MODEL-AD. We also work across disciplines to develop technologies that make these analyses available to a wide audience of researchers. Most notably, we recently celebrated the launch of Agora, an interactive, web-based explorer that provides access to research and analyses of nascent AD drug targets produced in conjunction with the NIH-led Accelerating Medicines Partnership.

Systems Biology

The Systems Biology research group at Sage Bionetworks is working to understand the underlying mechanisms causal to common disease. We use large-scale genomic analysis to identify disease subclasses, generate diagnostic and prognostic biomarkers, and to identify pathophysiology causal to disease in collaboration with academic and industry partners. Our current portfolio is focused on neurobiology, spanning both neurodegenerative and neuropsychiatric disorders, and includes projects in other disease areas including immunology, metabolic disease and craniofacial deformation.

Technology Platforms & Services

We’re working on the tools and platforms required to gather, share and use biomedical data in novel ways. These are targeted both at the research community, as well as organizations and individuals who are involved in providing data and being involved in the research process. They range from the technology platforms Synapse and BRIDGE, through novel methods of addressing governance issues around the distribution of human data such as E-Consent, to the ability to run Challenges to solve data-driven questions through our partnership with DREAM.