Clinical and Translational Science Award (CTSA)

New award will coalesce and coordinate informatics activities across the Clinical and Translational Science Award (CTSA) Program to provide collaborative clinical and translational research infrastructure.

Clinical and Translational Science Award (CTSA)

Sage Bionetworks, in a broad partnership led by OHSU, has been awarded the new CTSA Program National Center for Data to Health (CD2H). This award will coalesce and coordinate informatics activities across the Clinical and Translational Science Award (CTSA) Program, a network of more than 50 medical research institutions, to provide collaborative clinical and translational research infrastructure.

The CTSA will be led by Dr. Melissa Haendel (OHSU), Dr. Kristi Holmes (Northwestern University), Dr. Sean Mooney (University of Washington), Dr. Christopher Chute (Johns Hopkins University School of Medicine), and John Wilbanks (Sage Bionetworks). “The goal is to unlock the amazing wealth of technologies and innovation located within each individual CTSA and to create cohesive communities of practice founded on the fundamental premise that team science, data sharing, and collaborative innovation can advance patient care” described Dr. Melissa Haendel, the center director at Oregon Health & Sciences University.

The newly created center will focus on creating and harnessing an ecosystem for translational scientists to discover and share their software, data, and other research resources within the CTSA Program network. The CD2H also creates a social coding environment for translational science institutions, leveraging the community-driven DREAM challenges as a mechanism to stimulate innovation. Sage Bionetworks will bring community management and social engineering expertise to the program.

Dr. Justin Guinney, Sage Bionetworks Vice President of Computational Oncology and co-director of DREAM Challenges, shared, “The CTSA network is a vibrant community which can greatly benefit from a set of integrated platforms and best-practices across institutions to facilitate data sharing and method benchmarking. Our vision is that a data-driven and model-based ecosystem will have a lasting impact on patient outcomes.”

CTSA partners include Oregon Health & Science University, Northwestern University, University of Washington, Johns Hopkins University School of Medicine, and Sage Bionetworks, together with The Scripps Research Institute, Washington University in St. Louis, the University of Iowa, and The Jackson Laboratory. The program is supported by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (Grant U24TR002306).

Read more in related articles:


Other Collaborative Science research studies

Accelerating Medicine Partnership in Alzheimer’s Disease

AMP-AD is a public private partnership designed to use systems biology to identify novel targets for AD treatment.

Learn More

The ICGC-TCGA Whole Genome Pan-Cancer Analysis Working Group

The Pan-Cancer Analysis of Whole Genomes (PCAWG) is an effort to combine all ICGC and TCGA whole genome sequencing data to collaboratively attain an integrated understanding of cancer by deriving insights across tumor types.

Learn More


Synodos is a first-of-its-kind Neurofibromatosis research collaboration dedicated to defeating the rare genetic disorder neurofibromatosis.

Learn More