October 24A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection
October 22Spatiotemporal loss of NF1 in Schwann cell lineage leads to different types of cutaneous neurofibroma susceptible to modification by the Hippo pathway
September 11The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer’s disease
September 5The Healthy Pregnancy Research Program: transforming pregnancy research through a ResearchKit app
August 21The accuracy of passive phone sensors in predicting daily mood
August 20Probing the chemical–biological relationship space with the Drug Target Explorer
August 9Using Mobile Apps to Assess and Treat Depression in Hispanic and Latino Populations: Fully Remote Randomized Clinical Trial.
August 7A multi-omic atlas of the human frontal cortex for aging and Alzheimer’s disease research
August 1The Emerging Imperative for a Consensus Approach Toward the Rating and Clinical Recommendation of Mental Health Apps
June 13Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2
June 12Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived schwann cells
June 8Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters
June 7Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS
May 22The asthma mobile health study, smartphone data collected using ResearchKit
April 26Cutaneous neurofibromas in the genomics era: current understanding and open questions
April 18Smartphone-Based Passive Assessment of Mobility in Depression: Challenges and Opportunities
April 1Introduction to the “Technology in Practice” Special Issue.
April 1Review and Comparison of Electronic Patient-Facing Family Health History Tools
March 7Engaging populations underrepresented in research through novel approaches to consent
February 1A community approach to mortality prediction in sepsis via gene expression analysis
January 1Democratizing Health Data for Translational Research
December 21The inconvenience of data of convenience: computational research beyond post-mortem analyses
October 23KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer
October 17Targeted metabolomics and medication classification data from participants in the ADNI1 cohort
October 16The efficacy of smartphone-based mental health interventions for depressive symptoms: a meta-analysis of randomized controlled trials
October 10An xQTL map integrates the genetic architecture of the human brain’s transcriptome and epigenome
September 28Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology
August 30Consent Processes for Mobile App Mediated Research: Systematic Review
August 29Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells
August 3Cancer: A precision approach to tumour treatment
June 1Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression
June 1AACR Project GENIE: Powering Precision Medicine Through An International Consortium.
May 1Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study
April 11A high-throughput molecular data resource for Cutaneous Neurofibromas
March 28Molecular, phenotypic, and sample-associated data to describe pluripotent stem cell lines and derivatives
February 16Formative Evaluation of Participant Experience With Mobile eConsent in the App-Mediated Parkinson mPower Study: A Mixed Methods Study
February 14The Mole Mapper Study, mobile phone skin imaging and melanoma risk data collected using ResearchKit
January 4Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer
December 19Differential gene expression profiling of matched primary renal cell carcinoma and metastases reveals upregulation of extracellular matrix genes
December 1Systems Approaches to Cancer Biology
November 15Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data
October 11Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases.
September 26Gene expression elucidates functional impact of polygenic risk for schizophrenia
August 23Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis
July 15Crowdsourcing biomedical research: leveraging communities as innovation engines
July 11Spatiotemporal reconstruction of the human blastocyst by single-cell gene expression analysis informs induction of naive pluripotency
July 6Mobile health: the power of wearables, sensors, and apps to transform clinical trials
June 10Crowdsourced estimation of cognitive decline and resilience in Alzheimer’s disease
June 9Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cell from the Progenitor Cell Biology Consortium
June 3Understanding the contribution of family history to colorectal cancer risk and its clinical implications: A state-of-the-science review
May 5Developing a Transparent, Participant-Navigated Electronic Informed Consent for Mobile-Mediated Research
April 11Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases
April 8DREAMTools: a Python package for scoring collaborative challenges
March 15A large dataset of protein dynamics in the mammalian heart proteome
March 3First, design for data sharing.
March 3The mPower study, Parkinson disease mobile data collected using ResearchKit.
March 3Smartphones as new tools in the management and understanding of Parkinson’s disease.
March 1Practical Guidelines for High-resolution Epigenomic Profiling of Postmortem Human Brain Tissue
February 22Empirical assessment of causal network inference through a community-based effort.
November 25The PsychENCODE project
October 12The consensus molecular subtypes of colorectal cancer.
September 7rCGH : a comprehensive array-based genomic profile platform for precision medicine
August 26TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability
July 13The NIH BD2K center for big data in translational genomics
July 12App-enabled trial participation: Tectonic shift or tepid rumble?
June 5Safety and Activity of the First-in-Class Sym004 Anti-EGFR Antibody Mixture in Patients with Refractory Colorectal Cancer.
May 18Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection.
May 12Heterogeneity of driver genes and therapeutic implications in colorectal cancer.
April 27Personalizing Colon Cancer Adjuvant Therapy: Selecting Optimal Treatments for Individual Patients.
March 16The Prostate Cancer DREAM Challenge: A Community-Wide Effort to Use Open Clinical Trial Data for the Quantitative Prediction of Outcomes in Metastatic Prostate Cancer.
February 18Sparse expression bases in cancer reveal tumor drivers.
February 7Assessing the scale of tumor heterogeneity by complete hierarchical segmentation of MRI.
February 5Database of genomic biomarkers for cancer drugs and clinical targetability in solid tumors.
January 28Bayesian Network Reconstruction using Systems Genetics Data: Comparison of MCMC Methods.
January 15Diversity matters: Historical lessons.
December 23Impact of centralization on aCGH-based genomic profiles for precision medicine in oncology.
December 14Response to “Tumor cells in search for glutamate: an alternative explanation for increased invasiveness of IDH1 mutant gliomas”.
November 11Social interactomes for enabling research communities.
October 28Patient-specific metrics of invasiveness reveal significant prognostic benefit of resection in a predictable subset of gliomas.
October 8Molecular Markers Identify Subtypes of Stage III Colon Cancer Associated with Patient Outcomes.
October 7Simulation studies as designed experiments: the comparison of penalizede regression models in the “large p, small n” setting.
October 1Large-scale evaluation of ANTs and FreeSurfer cortical thickness measurements.
September 10Game design for bioinformatics and cyberinfrastructure learning: a parallel computing case study.
September 10Piecing the puzzle together: a revisit to transcript reconstruction problem in RNA-Seq.
September 5Phase I/IIa study evaluating the safety, efficacy, pharmacokinetics, and pharmacodynamics of lucitanib in advanced solid tumors.
September 1Drug susceptibility prediction against a panel of drugs using kernelized Bayesian multitask learning.
August 19Periostin is a novel therapeutic target that predicts and regulates glioma malignancy.
August 15Functional kinomics identifies candidate therapeutic targets in head and neck cancer.
August 14Multiplatform Analysis of 12 Cancer Types Reveals Molecular Classification within and across Tissues of Origin.
July 30Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases.
July 16Mapping sleeping bees within their nest: spatial and temporal analysis of worker honey bee sleep.
July 15Optimal design of trials to demonstrate the utility of genomically-guided therapy: putting Precision Cancer Medicine to the test.
June 22Assessing the clinical utility of cancer genomic and proteomic data across tumor types.
June 16Invasion and proliferation kinetics in enhancing gliomas predict IDH1 mutation status.
May 30Clues from the resilient.
May 27Describing high-order statistical dependence using “Concurrence Topology,” with application to functional MRI brain data.
May 6Citizens as partners in the use of clinical data.
May 1TGR analysis in phase I clinical trials–letter.
May 1CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer.
April 4Standardized decision support in next generation sequencing reports of somatic cancer variants.
March 30Synapse elimination and learning rules co-regulated by MHC class I H2-Db.
March 27Global optimization of somatic variant identification in cancer genomes with a global community challenge.
March 1Coupled dimensionality reduction and classification for supervised and semi-supervised multi label learning.
March 1Synthetic lethal screens as a means to understand and treat MYC-driven cancers.
January 31ANKS1B is a smoking-related molecular alteration in clear cell renal cell carcinoma.
January 23Discriminating survival outcomes in patients with glioblastoma using a simulation-based, patient-specific response metric
January 19Systematic assessment of analytical methods for drug sensitivity prediction from cancer cell line data.
January 18The Stream Algorithm: computationally efficient ridge-regression via Bayesian model averaging, and applications to pharmacogenomic prediction of cancer cell line sensitivity
January 18Stepwise Group Sparse Regression (SGSR): Gene-Set-Based Pharmacogenomic Predictive Models with Stepwise Selection of Functional Priors.
January 17Bayesian Multiview Dimensionality Reduction for Learning Predictive Subspaces.
January 17Embedding Heterogeneous Data by Preserving Multiple Kernels.
January 17The Stream Algorithm: computationally efficient ridge-regression via Bayesian model averaging, and applications to pharmacogenomic prediction of cancer cell line sensitivity.
January 14The evolution of our molecular understanding of colorectal cancer: what we are doing now, what the future holds, and how tumor profiling is just the beginning.
January 1Systematic assessment of analytical methods for drug sensitivity prediction from cancer cell line data.
December 18Somatic Expression of ENRAGE is Associated with Obesity Status among Patients with Clear Cell Renal Cell Carcinoma
December 13Network-based differential gene expression analysis suggests cell cycle related genes regulated by E2F1 underlie the molecular difference between smoker and non-smoker lung adenocarcinoma
December 12Modeling RAS Phenotype in Colorectal Cancer Uncovers Novel Molecular Traits of RAS Dependency and Improves Prediction of Response to Targeted Agents in Patients.
November 15Cancer, Potential of the synthetic lethality principle
November 15MyoD is a tumor suppressor gene in medulloblastoma
November 13Tumor Growth Rate is an early indicator of anti-tumor drug activity in phase I trials
September 26The Cancer Genome Atlas Pan-Cancer analysis project
September 26Enabling Transparent and Collaborative Computational Analysis of 12 tumor types within The Cancer Genome Atlas
September 2HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism
August 28A statin-dependent QTL for GATM expression is associated with statin-induced myopathy
August 26Comparison of Outcomes After Fluorouracil-Based Adjuvant Therapy for Stage II and III Colon Cancer Between 1978-1995 and 1996-2007: Findings from the ACCENT Database
August 15Impact of bioinformatic procedures in the development and translation of high-throughput molecular classifiers in clinical oncology
August 10Parallel globally optimal structure learning of Bayesian networks
August 10Tumor Growth Rate Provides Useful Information to Evaluate Sorafenib and Everolimus Treatment in Metastatic Renal Cell Carcinoma Patients: An Integrated Analysis of the TARGET and RECORD Phase 3 Trial Data.
August 9Integrative Modeling of eQTLs and Cis-Regulatory Elements Suggests Mechanisms Underlying Cell Type Specificity of eQTLs
July 18A phase II flexible screening design allowing for interim analysis and comparison with historical control
June 25hARACNe: improving the accuracy of regulatory model reverse engineering via higher order data processing inequality tests
May 9Genome-wide Characterization of Transcriptional Patterns in High and Low Antibody Responders to Rubella Vaccination
May 9Improving Breast Cancer Survival Analysis Through Competition-Based Multidimensional Modeling
May 2IGF-1R targeting increases the antitumor effects of DNA damaging agents in SCLC model: an opportunity to increase the efficacy of standard therapy
May 1Systematic Analysis of Challenge-Driven Improvements in Molecular Prognostic Models for Breast Cancer
April 26Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge
April 25Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
April 15A network-heuristic approach to improve the impact of genomic data on drug discovery
April 9Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer’s disease.
April 5Metcalfe’s law and the biology information commons
March 28A Fool’s Errand
March 28A system biology framework identifies molecular underpinings of coronary heart disease
March 18Modeling causality for pairs of phenotypes in systems genetics
March 18clearScience: Infrastructure for communicating Data-intensive science
March 15US-EU Scientific Research Collaborations: Sage Bionetworks’ Experience Navigating the Complex Regulatory Landscape.
February 11Response classification based on a minimal model of glioblastoma growth is prognostic for clinical outcomes and distinguishes progression from pseudoprogression
January 16GSVA: Gene Set Variation Analysis
February 16Dummy Pub: 2012