Clinical and Translational Science Award (CTSA)

Accelerating advancements in informatics by promoting data reuse and interoperability, tool sharing, informatics fluency, and collaboration

Sage Bionetworks, in a broad partnership led by OHSU, was awarded the CTSA Program National Center for Data to Health (CD2H). This award coalesces and coordinates informatics activities across the Clinical and Translational Science Award (CTSA) Program, a network of more than 50 medical research institutions, to provide collaborative clinical and translational research infrastructure.

The CTSA is led by Dr. Melissa Haendel (OHSU), Dr. Kristi Holmes (Northwestern University), Dr. Sean Mooney (University of Washington), Dr. Christopher Chute (Johns Hopkins University School of Medicine), and Dr. Justin Guinney (Sage Bionetworks).

The center focuses on creating and harnessing an ecosystem for translational scientists to discover and share their software, data, and other research resources within the CTSA Program network. The CD2H also creates a social coding environment for translational science institutions, leveraging the community-driven DREAM Challenges as a mechanism to stimulate innovation. Sage Bionetworks brings community management and social engineering expertise to the program.

Dr. Justin Guinney, Sage Bionetworks Vice President of Computational Oncology and co-director of DREAM Challenges, shared, “The CTSA network is a vibrant community which can greatly benefit from a set of integrated platforms and best-practices across institutions to facilitate data sharing and method benchmarking. Our vision is that a data-driven and model-based ecosystem will have a lasting impact on patient outcomes.”

Visit the CD2H site

CTSA partners include Oregon Health & Science University, Northwestern University, University of Washington, Johns Hopkins University School of Medicine, and Sage Bionetworks, together with The Scripps Research Institute, Washington University in St. Louis, the University of Iowa, and The Jackson Laboratory. The program is supported by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (Grant U24TR002306).