ICGC-TCGA DREAM Somatic Mutation Calling – RNA Challenge

An international effort to improve standard methods for identifying cancer-associated rearrangements in RNA sequencing (RNA-seq) data

The ICGC-TCGA DREAM Somatic Mutation Calling – RNA (SMC-RNA) Challenge is a community-based collaborative competition of researchers from across the world charged to rigorously assess the accuracy of methods used in cancer-associated RNA-seq analysis, with focus in two areas: quantification of known isoforms and detection of novel fusion transcripts. The SMC-RNA Challenge will analyze dozens of samples created to have known alterations representing different tumor types, allowing confidence that the winning methods will be generalizable across the broad range of human cancers.