Multiple Myeloma DREAM Challenge

Accelerating the development and evaluation of models for risk stratification of patients to improve therapeutic decision-making

Multiple myeloma (MM) is a cancer of the plasma cells in the bone marrow, and its clinical course depends on a complex interplay of clinical traits and molecular characteristics of the plasma cells. Since risk-adapted therapy is becoming standard of care, there is an urgent need for a precise risk stratification model to assist in therapeutic decision-making. While progress has been made, there remains a significant opportunity to improve patient stratification to optimize treatment and to develop new therapies for high-risk patients. The MM DREAM Challenge aims to accelerate the development and evaluation of such risk models in multiple myeloma.