ICGC-TCGA Whole Genome Pan-Cancer Analysis Working Group
Combining ICGC and TCGA whole genome sequencing data to get an integrated understanding of cancer across tumor types
In 2013, Sage assisted with the coordination of The Cancer Genome Atlas (TCGA) pan-cancer analysis by hosting and coordinating the outputs of 65 different analytical workflows using the open source software platform developed by Sage, called Synapse, which data scientists can use to carry out, track, and communicate their research in real time. Since then, all TCGA working groups have been using Synapse to coordinate their analysis outputs during the research process and preparation of manuscripts.
In 2015, the International Cancer Genome Consortium (ICGC) and TCGA partnered for a joint analysis of over 800 terabytes of data from 1,350 cancer whole genomes. The group used infrastructure and techniques developed by Sage Bionetworks to coordinate distribution of data and analytical results of the more than 400 researchers involved in the project.