Synapse is a technology platform developed by Sage Bionetworks for research teams to organize data, track analyses, and collaborate across organizational boundaries. Synapse is designed according to the Findable, Accessible, Interoperable, Reusable (FAIR) principles, making research teams more productive while supporting discovery, access, and reuse by the broader scientific community. The Synapse technology stack is REST-based, modular, and built from industry-standard components, intended to leverage public platforms and tools such as cloud storage and compute, data repositories, data visualization tools, and analytical tools such as RStudio and Jupyter Notebooks. The Sage team supports integrations with external systems. Synapse provides HIPAA-compliant security and data governance tools to ensure data is protected and accessible to scientists while respecting patients’ rights.

At Sage Bionetworks, we use Synapse across a diverse array of projects to make biomedical research more transparent,reproducible and accessible to a broader audience. Synapse is freely available for use by external researchers and serves as the host site for scientific collaborations, individual research projects, and DREAM challenges. For more information, visit Synapse.org.